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KMID : 0861020020170010013
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Korea Journal of Herbology
2002 Volume.17 No. 1 p.13 ~ p.28
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Experimental Studies on the Haematopoietic Effects of the Carthami Flos
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徐榮培/Seo, Young-Bae
李龍求/李永喆/閔平基/Lee, Yong-Koo/Lee, Young-Cheol/Min, Pyung-Gee
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Abstract
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In order to investigate the haematopoietic effects of Carthami Flos on various experiments were studied.
The results were obtained as follows:
1. In the proliferous effect of bone marrow cells, water extracts of Carthami Flos played an important role on the proliferating bone marrow cells compared with control group at low density.
2. The water extracts of Carthami Flos promoted the proliferation of the bone marrow cells into cluster, BFU-E, CFU-GEMM and colony.
3. In the bone marrow cells treated with CTX, the water extracts of Carthami Flos promoted the SCF, EPO, IL-4, IL-6 gene expression, but gene expression of its receptors, c-kit, EPO-R, TPO, c-mpl, EKLF, GATA-1 were not promoted significantly.
According to the above results, water extracts of Cathami Flos promoted not only the differentiation
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